Author

S. Kitamura

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 3 Approach:experimental assay· 3 Organism:human· 3 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

D. W. Wolan· 3 shared A. Bergano· 1 shared A. K. Chatterjee· 1 shared A. R. Ramos· 1 shared A. Takamura· 1 shared B. D. Hammock· 1 shared B. F. Cravatt· 1 shared B. Lee· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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3 shared papersBiochemistry

D. W. Wolan

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

PROTAC-mediated selective degradation of cytosolic soluble epoxide hydrolase enhances ER-stress reduction

Y. Wang, C. Morisseau, A. Takamura, D. Wan, D. Li, S. Sidoli, J. Yang, D. W. Wolan, B. D. Hammock, S. Kitamura

This paper develops first-in-class PROTACs that selectively degrade cytosolic sEH, reducing ER stress more effectively than sEH inhibitors.

bioRxiv · Jan 20, 2022 · PreprintBiochemistry

Chemical inhibition of ENL/AF9 YEATS domains in acute leukemia

L. Garnar-Wortzel, T. R. Bishop, S. Kitamura, N. Milosevich, J. N. Asiaban, X. Zhang, Q. Zheng, E. Chen, A. R. Ramos, C. J. Ackerman, E. N. Hampton, A. K. Chatterjee, T. S. Young, M. V. Hull, K. B. Sharpless, , M. A. Erb

This study identifies a potent inhibitor of the ENL/AF9 YEATS domain and demonstrates its selective suppression of ENL-dependent leukemia genes.

bioRxiv · Dec 1, 2020Cancer Biology

An influenza A hemagglutinin small-molecule fusion inhibitor identified by a new high-throughput fluorescence polarization screen.

Y. Yao, R. U. Kadam, C.-C. D. Lee, J. L. Woehl, N. C. Wu, X. Zhu, S. Kitamura, I. A. Wilson, D. W. Wolan

This paper identifies a small-molecule inhibitor of influenza A HA stem fusion using a fluorescence polarization screen and validates its antiviral activity against multiple H1N1 and H5N1 strains.

bioRxiv · Apr 2, 2020Biophysics

Transcriptome stability profiling identifies novel and functional MIRNA targets in melanoma cells

P. Joshi, T. Seki, S. Kitamura, A. Bergano, B. Lee, R. J. Perera

The paper uses RNA stability profiling to identify novel miR-211 targets in melanoma cells and validates their functional role in cell invasion and colony formation.

bioRxiv · Jun 1, 2019Cancer Biology