Author

T. Spector

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Biochemistry· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Organism:human· 6 Assay:metagenomics· 5 Approach:statistical model· 4 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

C. I. Le Roy· 2 shared C. Steves· 2 shared J. T. Bell· 2 shared A. Franke· 1 shared A. Gardere· 1 shared A. Peters· 1 shared A. R. Geelen· 1 shared A. Reyes· 1 shared

Activity by Year

2019-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersMicrobiology

C. I. Le Roy

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Impacts of dietary exposure to pesticides on faecal microbiome metabolism in adult twins

R. Mesnage, R. C. E. Bowyer, S. El Balkhi, F. Saint-Marcoux, A. Gardere, Q. R. Ducarmon, A. R. Geelen, R. D. Zwittink, D. Tsoukalas, E. Sarandi, E. I. Paramera, T. Spector, C. Steves, M. Antoniou

This study links pesticide exposure to changes in gut microbiome composition and function in adult twins using urinary biomarkers and metagenomic/metabolomic analyses.

bioRxiv · Jun 16, 2021Pharmacology & Toxicology

Strain-level analysis of Bifidobacterium spp. from gut microbiomes of adults of differing lactase persistence genotypes

V. Schmidt, H. Enav, T. Spector, N. D. Youngblut, R. Ley

This study analyzes Bifidobacterium strains in gut microbiomes of adults with different lactase persistence genotypes, finding no effect of LCT genotype on strain composition but intra-individual stability and twin-related strain sharing.

bioRxiv · Jul 16, 2020Microbiology

Host genetic and environmental factors shape the human gut resistome

C. I. Le Roy, R. C. Bowyer, V. R. Carr, R. Costeira, J. E. R. Castillo-Fernandez, T. C. Martin, T. Spector, C. Steves, D. Moyes, S. K. Forslund, J. T. Bell

This study quantifies the genetic and environmental influences on the human gut resistome using metagenomic data from twins, finding 25% heritability and strong associations with lifestyle factors.

bioRxiv · May 18, 2020 · PreprintMicrobiology

Arrhythmic gut microbiome signatures for risk profiling of Type-2 Diabetes

S. Reitmeier, S. Kiessling, T. Clavel, M. List, E. L. Almeida, T. G. Ghosh, K. Neuhaus, M. Troll, H. Grallert, W. Rathmann, B. Linkohr, A. Franke, C. I. Le Roy, J. Bell, T. Spector, , D. Haller

The paper identifies arrhythmic gut microbiome signatures associated with Type-2 Diabetes risk and validates them in a separate cohort.

bioRxiv · Dec 27, 2019Microbiology

Global variability of the human IgG glycome

J. Stambuk, N. Nakic, F. Vuckovic, M. Pucic-Bakovic, G. Razdorov, I. Trbojevic-Akmacic, M. Novokmet, T. Keser, M. Vilaj, T. Pavic, I. Gudelj, M. Simurina, M. Song, H. Wang, M. Pericic Salihovic, , G. Lauc

The paper analyzes global variability in IgG glycosylation across populations, finding that country of residence and socioeconomic development strongly influence glycan features and monogalactosylation levels.

bioRxiv · Feb 1, 2019Biochemistry

The virome in adult monozygotic twins with concordant or discordant gut microbiomes

J. L. Moreno-Gallego, S.-P. Chou, S. C. Di Rienzi, J. K. Goodrich, T. Spector, J. T. Bell, N. Youngblut, I. Hewson, A. Reyes, R. E. Ley

This study examines the relationship between microbiome diversity and virome diversity in adult monozygotic twins, finding that microbiome discordance correlates with virome dissimilarity.

bioRxiv · Jan 2, 2019 · PreprintMicrobiology