Author

R. Ley

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Immunology· 1

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Research Focus:cell type annotation· 4 Organism:human· 3 Assay:metagenomics· 3 Approach:statistical model· 3 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1

Frequent Co-Authors

N. D. Youngblut· 3 shared J. Waters· 2 shared A. Drager· 1 shared A. H. Dilmore· 1 shared A. Janzon· 1 shared A. T. Gewirtz· 1 shared A. Tyakht· 1 shared Alzheimer Gut Microbiome Project Consortium· 1 shared

Activity by Year

2019-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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3 shared papersMicrobiology

N. D. Youngblut

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Author profile →

5 papers

Recent·Most cited

Medication Use is Associated with Distinct Microbial Features in Anxiety and Depression

A. H. Dilmore, R. Kuplicki, D. McDonald, M. Kumar, M. Estaki, N. D. Youngblut, A. Tyakht, G. Ackermann, C. Blach, S. MahmoudianDehkordi, B. Dunlop, S. Bhattacharyya, S. Guinjoan, P. Mandaviya, R. Ley, , Alzheimer Gut Microbiome Project Consortium

This study links medication use to distinct gut microbial features in anxiety and depression, showing antidepressants have a larger effect on microbiota than diagnoses.

Molecular Psychiatry · Jan 10, 2025Peer-reviewedMicrobiology

An integrated systems-biology platform for power-to-gas technology

I. Casini, T. McCubbin, S. Esquivel-Elizondo, G. G. Luque, D. Evseeva, C. Fink, S. Beblawy, N. D. Youngblut, L. Aristilde, D. Huson, A. Drager, R. Ley, E. Marcellin, L. T. Angenent, B. Molitor

This paper develops a systems-biology platform for Methanothermobacter spp. to optimize power-to-gas technology by analyzing genome-scale metabolic models and growth performance in bioreactors.

bioRxiv · Dec 30, 2022Microbiology

Strain-level analysis of Bifidobacterium spp. from gut microbiomes of adults of differing lactase persistence genotypes

V. Schmidt, H. Enav, T. Spector, N. D. Youngblut, R. Ley

This study analyzes Bifidobacterium strains in gut microbiomes of adults with different lactase persistence genotypes, finding no effect of LCT genotype on strain composition but intra-individual stability and twin-related strain sharing.

bioRxiv · Jul 16, 2020Microbiology

Interactions between the gut microbiome and mucosal immunoglobulins A, M and G in the developing infant gut

A. Janzon, J. K. Goodrich, O. Koren, the TEDDY study group, J. Waters, R. Ley

The paper examines how IgA, IgM, and IgG interact with the gut microbiome in infants, finding that IgA and IgM coat similar microbes while IgG targets different ones, and breastfeeding influences these interactions.

mSystems · Dec 17, 2019Peer-reviewedMicrobiology

Gut microbiota influence B cell function in a TLR5-dependent manner

S. Li, W. Walters, B. Chassaing, B. Zhang, Q. Shi, J. Waters, A. T. Gewirtz, C. A. Leifer, R. Ley

This study shows TLR5 signaling in epithelial cells affects B cell populations and antibody responses, leading to microbiome dysbiosis in TLR5-deficient mice.

bioRxiv · Feb 7, 2019 · PreprintImmunology