Author

T. Steinbrecher

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:plant (other)· 1 Assay:protein structure· 1

Frequent Co-Authors

C. Negron· 1 shared D. Tarkowska· 1 shared G. Leubner-Metzger· 1 shared G. Theissen· 1 shared I. Petrik· 1 shared J. D. Chodera· 1 shared J. O. Chandler· 1 shared K. Graeber· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

C. Negron

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Author profile →

2 papers

Recent·Most cited

The dimorphic diaspore model Aethionema arabicum (Brassicaceae): Distinct molecular and morphological control of responses to parental and germination temperatures

J. O. Chandler, P. K. I. Wilhelmsson, N. Fernandez-Pozo, K. Graeber, W. Arshad, M. Perez, T. Steinbrecher, K. K. Ullrich, T.-P. Nguyen, Z. Merai, K. Mummenhoff, G. Theissen, M. Strnad, O. Mittelsten Scheid, M. E. Schranz, , G. Leubner-Metzger

The paper investigates how parental and germination temperatures affect molecular and morphological responses in dimorphic diaspores of Aethionema arabicum, identifying gene expression and hormonal differences that regulate dormancy and germination.

bioRxiv · Dec 14, 2023 · PreprintPlant Biology

Predicting resistance of clinical Abl mutations to targeted kinase inhibitors using alchemical free-energy calculations

K. Hauser, C. Negron, S. K. Albanese, S. Ray, T. Steinbrecher, R. Abel, J. D. Chodera, L. Wang

This paper uses alchemical free-energy calculations to predict how Abl mutations affect inhibitor affinity, achieving accurate results for clinical mutations.

bioRxiv · Apr 2, 2018Cancer Biology