BiophysicsbioRxiv
Alternative transcription cycle for bacterial RNA polymerase
T. T. Harden, K. S. Herlambang, M. Chamberlain…·J. Gelles
The paper observes bacterial RNA polymerase (RNAP) remaining bound to DNA after termination and restarting transcription in reverse, producing antisense transcripts, using single-molecule fluorescence microscopy and genome-wide RNA sequencing.
DOI 10.1038/s41467-019-14208-9