Precise immunofluorescence canceling for highly multiplexed imaging capturing specific cell state
K. Tomimatsu, T. Fujii, R. Bise, K. Hosoda, Y. Taniguchi, H. Ochiai, H. Ohishi, K. Ando, R. Minami, T. Taro, K. Tanaka, S. Mori, A. Harada, K. Maehara, M. Nagasaki, , Y. Ohkawa
The paper introduces PECAbs for high-specificity multiplexed imaging of cell states and combines them with seq-smFISH to classify cells and identify signal activation states in human tissue.
bioRxiv · Oct 17, 2023 · PreprintCell Biology