MicrobiologyScience AdvancesPeer-reviewed
Toxic Small Alarmone Synthetase FaRel2 inhibits translation by pyrophosphorylating tRNAGly and tRNAThr
Tatsuaki Kurata, Masaki Takegawa, Takayuki Ohira…·Vasili Hauryliuk
The paper shows FaRel2, a toxSAS, specifically targets tRNAGly and tRNAThr by recognizing the acceptor stem, with structural differences explaining specificity variations among toxSASs.
5 citations