PhysiologybioRxivPreprint
Skeletal muscle aging drives sex- and compartment-specific protein insolubility that is modifiable by proteostasis-directed treatments
Paulo H.C. Mesquita, Tanisha Goyal, Xiayou Ren…·Benjamin F. Miller
This study investigates age-related changes in protein insolubility in skeletal muscle and shows that these changes are sex- and compartment-specific and can be modified by exercise and rapamycin.
DOI 10.64898/2026.10.29.762839