Molecular BiologybioRxivPreprint
Stalling of elongating Pol II triggers Ser7 phosphorylation in trans to drive transcription recovery
Iván Shlamovitz, Yu Bao, Tea Toteva…·Ana Tufegdžić Vidaković
The paper identifies a third mechanism for resolving stalled RNA polymerase II by showing that transcription stalling triggers GSK3-mediated phosphorylation of Ser7 on Pol II, which primes incoming Pol II for efficient elongation.