Author

Tenzin Tsepal

University of Massachusetts Chan Medical School

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:virus· 1

Frequent Co-Authors

Ala M. ShaqraiD· 1 shared Celia A. SchifferiD· 1 shared Daniel N. A. BoloniD· 1 shared Dustin DovalaiD· 1 shared Julia M. FlynniD· 1 shared Neşe Kurt YılmaziD· 1 shared Sarah N. ZvornicaniniD· 1 shared Stephanie A. MoquiniD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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9 top collaborators · 36 mutual co-author links

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1 shared paperBiochemistry

Ala M. ShaqraORCID

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1 paper

Recent·Most cited

BiochemistryACS Infectious DiseasesPeer-reviewedMar 12, 2024

Contributions of hyperactive mutations in Mpro from SARS-CoV-2 to drug resistance

Julia M. Flynn, Sarah N. Zvornicanin, Tenzin Tsepal…·Daniel N. A. Bolon

This study identifies hyperactive mutations in SARS-CoV-2 Mpro that increase enzyme activity and contribute to drug resistance, finding them more prevalent than binding-reducing mutations.

23 citationstop 2%

virusexperimental assay

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