Author

Thea A. Egelhofer

University of California, Santa Cruz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 1 Genetics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 3 Approach:experimental assay· 3 Research Focus:differential expression· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Andreas RechtsteineriD· 2 shared Susan StromeiD· 2 shared Alexander Maxwell BurroughsiD· 1 shared Andrew Kekūpaʻa KnutsoniD· 1 shared Jacob M. GarriguesiD· 1 shared Joshua A. ArribereiD· 1 shared Lakshminarayanan AravindiD· 1 shared Lisa N. PetrellaiD· 1 shared

Activity by Year

2017-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersGenetics

Andreas RechtsteinerORCID

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3 papers

Recent·Most cited

Molecular BiologyCell ReportsPeer-reviewedMar 1, 2020

NONU-1 encodes a conserved endonuclease required for mRNA translation surveillance

Marissa L. Glover, Alexander Maxwell Burroughs, Parissa C. Monem…·Joshua A. Arribere

The paper identifies NONU-1 as an endoribonuclease essential for translation surveillance pathways and shows its conservation across species.

87 citationstop 4%

C. elegansyeast

𝕏 PostBluesky

GeneticsbioRxivPreprintDec 17, 2018

LIN-15B promotes enrichment of H3K9me2 on the promoters of a subset of germline genes that are repressed in somatic cells in C. elegans

Andreas Rechtsteiner, Meghan E. Costello, Thea A. Egelhofer…·Lisa N. Petrella

The paper shows LIN-15B promotes H3K9me2 enrichment on germline gene promoters, repressing them in somatic cells, with distinct effects compared to DREAM complex mutants.

2 citations

C. elegansChIP-seq

𝕏 PostBluesky

Developmental BiologyGeneticsPeer-reviewedMar 3, 2017

Germ granules prevent accumulation of somatic transcripts in the adult C. elegans germline

Andrew Kekūpaʻa Knutson, Thea A. Egelhofer, Andreas Rechtsteiner, Susan Strome

This study shows that P granules in C. elegans prevent the accumulation of somatic transcripts in adult germ cells by down-regulating spermatogenesis RNAs and maintaining germ cell fate.

63 citations

C. elegansbulk RNA-seq

𝕏 PostBluesky