NeurosciencebioRxivPreprint
Axonal transcriptome reveals upregulation of PLK1 as a protective mechanism in response to increased DNA damage in FUSP525L spinal motor neurons
Vitaly L. Zimyanin, Banaja P. Dash, Dajana Großmann…·Andreas Hermann
The paper uses compartment-specific RNA-sequencing to analyze axonal and somatodendritic transcriptomes of FUS-ALS motor neurons, identifying PLK1 upregulation as a protective response to DNA damage.