BioinformaticsbioRxivPreprint
Supervised non-negative matrix factorization on cell-free DNA fragmentomic features enhances early cancer detection
Trung Hieu Tran, Ngoc Tan Pham, Van Thien Chi Nguyen…·Trong Hieu Nguyen
This paper uses supervised non-negative matrix factorization on cfDNA fragmentomic features to improve early cancer detection, achieving high AUC scores in both pan-cancer and HCC-specific classifications.
DOI 10.1101/2024.12.20.629316