Author

Trung Hieu Tran

Gene Solutions (Vietnam)ORCID 0000-0002-3989-4502Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:DNA methylation· 2 Organism:human· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:graph neural network· 1 Approach:statistical model· 1

Frequent Co-Authors

Hoa GiangiD· 2 shared Hoai‐Nghia NguyeniD· 2 shared Le Son TraniD· 2 shared Minh‐Duy PhaniD· 2 shared Trong Hieu NguyeniD· 2 shared Van Thien Chi NguyeniD· 2 shared Dac Ho Vo· 1 shared Hoai-Nghia Nguyen· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersBioinformatics

Hoa GiangORCID

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintDec 20, 2024

Supervised non-negative matrix factorization on cell-free DNA fragmentomic features enhances early cancer detection

Trung Hieu Tran, Ngoc Tan Pham, Van Thien Chi Nguyen…·Trong Hieu Nguyen

This paper uses supervised non-negative matrix factorization on cfDNA fragmentomic features to improve early cancer detection, achieving high AUC scores in both pan-cancer and HCC-specific classifications.

DOI 10.1101/2024.12.20.629316

humanDNA methylation

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Cancer BiologyJournal of Translational MedicinePeer-reviewedJul 3, 2024

Tissue of origin detection for cancer tumor using low-depth cfDNA samples through combination of tumor-specific methylation atlas and genome-wide methylation density in graph convolutional neural networks

Trong Hieu Nguyen, Nhu Nhat Tan Doan, Trung Hieu Tran…·Minh‐Duy Phan

The paper develops a model combining tumor-specific methylation atlas and cfDNA features to improve tissue-of-origin detection in low-depth cfDNA samples.

21 citations

humanDNA methylation

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