BiochemistryCell chemical biologyPeer-reviewed
Structural and mechanistic analysis of covalent ligands targeting the RNA-binding protein NONO
Garrett L. Lindsey, Thomas K. Hockley, Alejandro Villa Gomez…·Benjamin F. Cravatt
This paper reports covalent ligands targeting the RNA-binding protein NONO, showing they stabilize mRNA interactions, remodel transcriptomes, and suppress cancer cell growth with high specificity.
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