ImmunologybioRxivPreprint
Immunomodulatory impact of PTPN11/SHP2-based vertical RAS-MAPK pathway inhibition in pancreatic cancer
Asma Y. Alrawashdeh, Xun Chen, Philipp Hafner…·Dietrich Alexander Ruess
This study investigates the immunomodulatory effects of SHP2-based vertical RAS pathway inhibition in pancreatic cancer, revealing both immune-activating and suppressive changes that evolve with treatment.