Author

Thorsten R. Klingen

Helmholtz Centre for Infection Research

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Research Focus:variant calling· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Alice Carolyn McHardyiD· 2 shared Gülşah GabrieliD· 2 shared Jens Uwe LoersiD· 2 shared Frank KlawonniD· 1 shared Kyra MooreniD· 1 shared Stephanie Stanelle‐BertramiD· 1 shared Susanne ReimeringiD· 1 shared Thomas KreyiD· 1 shared

Activity by Year

2018-2019 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 24 mutual co-author links

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2 shared papersBioinformatics

Alice Carolyn McHardyORCID

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2 papers

Recent·Most cited

BioinformaticsScientific ReportsPeer-reviewedApr 18, 2019

Structures and functions linked to genome-wide adaptation of human influenza A viruses

Thorsten R. Klingen, Jens Uwe Loers, Stephanie Stanelle‐Bertram…·Alice Carolyn McHardy

The paper compares genome-wide adaptation of H3N2 and pH1N1 influenza A viruses, identifying regions under positive selection and linking them to host adaptation and drug resistance.

7 citations

humanwhole-genome sequencing

𝕏 PostBluesky

BioinformaticsScientific ReportsPeer-reviewedJan 4, 2018

Sweep Dynamics (SD) plots: Computational identification of selective sweeps to monitor the adaptation of influenza A viruses

Thorsten R. Klingen, Susanne Reimering, Jens Uwe Loers…·Alice Carolyn McHardy

The paper introduces SD plots to identify selective sweeps in influenza A virus genomes, showing their use in tracking adaptive changes in pH1N1 and sH3N2 viruses.

36 citationstop 4%

humanwhole-genome sequencing

𝕏 PostBluesky