Cell BiologybioRxivPreprint
SIRT3-dependent mitochondrial oxidative stress in sodium fluoride-induced hepatotoxicity and salvage by melatonin
Chao Song, Jiamin Zhao, Jingcheng Zhang…·Yong Zhang
This study shows melatonin reduces fluoride-induced oxidative stress in HepG2 cells and mice by enhancing SIRT3 activity and PGC-1/ERR-mediated SIRT3 expression.