Author

Tobias L Lenz

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Evolutionary Biology· 1

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Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1 Assay:whole-exome sequencing· 1

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Daniel M Jordan· 1 shared Shamil R Sunyaev· 1 shared Victor Spirin· 1 shared

Activity by Year

2016-2016 · peak 1/yr

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1 shared paperEvolutionary Biology

Daniel M Jordan

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1 paper

Recent·Most cited

Evolutionary BiologybioRxivJun 15, 2016

Excess of deleterious mutations around HLA genes reveals evolutionary cost of balancing selection

Tobias L Lenz, Victor Spirin, Daniel M Jordan, Shamil R Sunyaev

The paper investigates the impact of balancing selection around HLA genes, finding elevated frequencies of deleterious variants in linked non-HLA genes.

DOI 10.1093/molbev/msw127

humanwhole-exome sequencing

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