Author

Tobias Obser

University Medical Center Hamburg-Eppendorf

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Caroline KörösyiD· 1 shared Jan LipfertiD· 1 shared Maria Alexandra BrehmiD· 1 shared Stefanie D. PritzliD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperBiophysics

Caroline KörösyORCID

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1 paper

Recent·Most cited

BiophysicsJournal of Molecular BiologyPeer-reviewedSep 21, 2026

Magnetic Tweezers Experiments Reveal Increased Mechanical Sensitivity of the F2561Y Mutant in Von Willebrand Factor

Caroline Körösy, Stefanie D. Pritzl, Tobias Obser…·Jan Lipfert

This study uses magnetic tweezers to show the F2561Y mutation in VWF lowers stem opening force and increases open conformations, explaining its prothrombotic effects.

DOI 10.1016/j.jmb.2026.170028

humanexperimental assay

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