Cell BiologyCellular and Molecular Gastroenterology and HepatologyPeer-reviewed
TNF Receptor 1 regulates colonic mesenchymal cell diversity and the epithelial stem cell niche.
Safina Gadeock, Nandini Girish, Cambrian Y. Liu…·D. Brent Polk
This study shows TNFR1 promotes colonic mesenchymal cell diversity and stem cell niche function, with TNFR1 deficiency reducing cell diversity and impairing stem cell maintenance.