ImmunologybioRxiv
Airway epithelial cells and macrophages trigger IL-6-CD95/CD95L axis and mediate initial immunopathology of COVID-19
T. F. Fraga-Silva, U. G. Cipriano, M. J. Fumagalli…·V. L. D. Bonato
This study identifies the IL-6-CD95/CD95L axis as a key driver of immunopathology in severe COVID-19 through interactions between airway epithelial cells and macrophages.
DOI 10.1016/j.isci.2023.108366