Impairment of a distinct cancer-associated fibroblast population limits tumour growth and metastasis
U. Jungwirth, A. van Weverwijk, L. Jenkins, J. Alexander, D. Vicente, Q. Gao, S. Haider, M. Iravani, C. M. Isacke
The paper identifies a specific cancer-associated fibroblast subset that supports tumour growth and metastasis by expressing Endo180, and shows that targeting this subset can limit tumour progression.
bioRxiv · May 17, 2020Cancer Biology