Author

U. Kubitscheck

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 2 Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Assay:fluorescence / live-cell microscopy· 2 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

A. M. Krueger· 2 shared J. A. Ruland· 2 shared J. P. Siebrasse· 2 shared A. J. Peoples· 1 shared A. L. Spoering· 1 shared A. M. J. J. Bonvin· 1 shared A. Nitti· 1 shared B. J. A. Vermeulen· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersMicrobiology

A. M. Krueger

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A new antibiotic from an uncultured bacterium binds to an immutable target

R. Shukla, A. J. Peoples, K. C. Ludwig, S. Maity, M. G. N. Derks, A. M. Krueger, S. de Benedetti, B. J. A. Vermeulen, R. V. Honorato, F. Grein, F. Lavore, A. M. J. J. Bonvin, U. Kubitscheck, E. Breukink, C. Achorn, , M. Weingarth

This paper discovers a new antibiotic, clovibactin, from uncultured bacteria that targets pyrophosphate in bacterial cell wall precursors, effectively killing drug-resistant pathogens without resistance.

bioRxiv · May 15, 2023 · PreprintMicrobiology

Conformational coupling of the sialic acid TRAP transporter HiSiaQM with its substrate binding protein HiSiaP

M. F. Peter, J. A. Ruland, Y. Kim, P. Hendricks, J. P. Siebrasse, G. H. Thomas, U. Kubitscheck, G. Hagelueken

The paper demonstrates conformational coupling between the TRAP transporter HiSiaQM and its substrate binding protein HiSiaP using disulfide engineering and single-molecule TIRF microscopy.

bioRxiv · Mar 4, 2023Biochemistry

Nuclear export of the pre-60S ribosomal subunit through single nuclear pores observed in real time

J. A. Ruland, A. M. Krueger, K. E. Doerner, R. Bhatia, S. Wirths, D. Poetes, U. Kutay, J. P. Siebrasse, U. Kubitscheck

The paper observes the real-time nuclear export of pre-60S ribosomal subunits through single nuclear pores in living human cells, revealing kinetic details and mass flux rates.

bioRxiv · Mar 30, 2021Cell Biology