Author

V. Bohnert

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Cancer Biology· 1

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

A. J. Joseph· 1 shared F. B. Yu· 1 shared G. Skariah· 1 shared H. Goodarzi· 1 shared J. Swinderman· 1 shared L. A. Gilbert· 1 shared L. Li· 1 shared S. Wang· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

A. J. Joseph

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1 paper

Recent·Most cited

ENPP1 is an innate immune checkpoint of the anticancer cGAMP-STING pathway

S. Wang, V. Bohnert, A. J. Joseph, V. Sudaryo, J. Swinderman, F. B. Yu, X. Lyu, G. Skariah, V. Subramanyam, L. A. Gilbert, H. Goodarzi, L. Li

This study identifies ENPP1 as an innate immune checkpoint that suppresses the cGAMP-STING pathway, promoting tumor growth and metastasis, and shows that inhibiting its cGAMP hydrolase activity enhances cancer immunity.

bioRxiv · Jun 1, 2023 · PreprintCancer Biology