Author

J. Swinderman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Assay:scRNA-seq· 2 Assay:ATAC-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:clustering· 1 Approach:deep learning· 1

Frequent Co-Authors

L. A. Gilbert· 2 shared A. Choudhury· 1 shared A. J. Joseph· 1 shared A. Perry· 1 shared B. V. Lien· 1 shared C. D. Eaton· 1 shared D. A. Lim· 1 shared D. L. Swaney· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCancer Biology

L. A. Gilbert

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Author profile →

2 papers

Recent·Most cited

Epigenetic reprogramming shapes the cellular landscape of schwannoma

S. J. Liu, T. Casey-Clyde, N. W. Cho, J. Swinderman, M. Pekmezci, M. C. Dougherty, K. Foster, W. C. Chen, J. E. Villanueva-Meyer, D. L. Swaney, H. N. Vasudevan, A. Choudhury, J. D. Breshears, U. E. Lang, C. D. Eaton, , D. R. Raleigh

This study identifies two molecular groups in schwannomas driven by epigenetic reprogramming and shows ionizing radiation can reprogram neural crest to immune-enriched schwannomas.

Nature Communications · Jan 12, 2024Peer-reviewedCancer Biology

ENPP1 is an innate immune checkpoint of the anticancer cGAMP-STING pathway

S. Wang, V. Bohnert, A. J. Joseph, V. Sudaryo, J. Swinderman, F. B. Yu, X. Lyu, G. Skariah, V. Subramanyam, L. A. Gilbert, H. Goodarzi, L. Li

This study identifies ENPP1 as an innate immune checkpoint that suppresses the cGAMP-STING pathway, promoting tumor growth and metastasis, and shows that inhibiting its cGAMP hydrolase activity enhances cancer immunity.

bioRxiv · Jun 1, 2023 · PreprintCancer Biology