Author

L. A. Gilbert

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 4

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 4 Research Focus:cell type annotation· 2 Approach:deep learning· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1

Frequent Co-Authors

H. Goodarzi· 2 shared J. Swinderman· 2 shared A. Akhmanova· 1 shared A. Choudhury· 1 shared A. E. Prota· 1 shared A. J. Joseph· 1 shared A. Navickas· 1 shared A. Perry· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

H. Goodarzi

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Epigenetic reprogramming shapes the cellular landscape of schwannoma

S. J. Liu, T. Casey-Clyde, N. W. Cho, J. Swinderman, M. Pekmezci, M. C. Dougherty, K. Foster, W. C. Chen, J. E. Villanueva-Meyer, D. L. Swaney, H. N. Vasudevan, A. Choudhury, J. D. Breshears, U. E. Lang, C. D. Eaton, , D. R. Raleigh

This study identifies two molecular groups in schwannomas driven by epigenetic reprogramming and shows ionizing radiation can reprogram neural crest to immune-enriched schwannomas.

Nature Communications · Jan 12, 2024Peer-reviewedCancer Biology

ENPP1 is an innate immune checkpoint of the anticancer cGAMP-STING pathway

S. Wang, V. Bohnert, A. J. Joseph, V. Sudaryo, J. Swinderman, F. B. Yu, X. Lyu, G. Skariah, V. Subramanyam, L. A. Gilbert, H. Goodarzi, L. Li

This study identifies ENPP1 as an innate immune checkpoint that suppresses the cGAMP-STING pathway, promoting tumor growth and metastasis, and shows that inhibiting its cGAMP hydrolase activity enhances cancer immunity.

bioRxiv · Jun 1, 2023 · PreprintCancer Biology

Integrative identification of non-coding regulatory regions driving metastatic prostate cancer

B. J. Woo, R. Moussavi-Baygi, H. Karner, M. Karimzadeh, K. Garcia, T. Joshi, K. Yin, A. Navickas, L. A. Gilbert, B. Wang, H. Asgharian, F. Y. Feng, H. Goodarzi

This study identifies non-coding regulatory regions driving metastatic prostate cancer using an integrative computational and experimental approach.

bioRxiv · Apr 14, 2023Cancer Biology

Pharmaceutical-grade Rigosertib is a Microtubule-destabilizing Agent

M. Jost, Y. Chen, L. A. Gilbert, M. A. Horlbeck, L. Krenning, G. Menchon, A. Rai, M. Y. Cho, J. J. Stern, A. E. Prota, M. Kampmann, A. Akhmanova, M. O. Steinmetz, M. E. Tanenbaum, J. S. Weissman

This paper shows pharmaceutical-grade rigosertib, with high purity, causes microtubule destabilization in cells, confirming its mechanism of action against cancer cells.

bioRxiv · Jan 28, 2020Cancer Biology