Inhibition of Cellular MEK/ERK Signaling Suppresses Murine Papillomavirus Type 1 Replicative Activities and Promotes Tumor Regression
A. J. Luna, J. M. Young, R. T. Sterk, V. Bondu, F. A. Schultz, D. F. Kusewitt, H. Kang, M. A. Ozbun
This paper shows that MEK1/2 inhibitors reduce MmuPV1 replication and promote tumor regression in mice, suggesting MEK1/2 as a therapeutic target for papillomavirus diseases.
bioRxiv · Mar 14, 2023Cancer Biology