Author

V. Deretic

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Organism:human· 1

Frequent Co-Authors

G. S. Timmins· 2 shared B. S. Phinney· 1 shared C. Ye· 1 shared E. C. Clarke· 1 shared E. Hendrix· 1 shared E. Trosdal· 1 shared F. Wang· 1 shared J. Jia· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersMicrobiology

G. S. Timmins

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3 papers

Recent·Most cited

Noncanonical roles of ATG5 and membrane atg8ylation in retromer assembly and function

M. A. Paddar, F. Wang, E. Trosdal, E. Hendrix, Y. He, M. R. Salemi, M. Mudd, J. Jia, T. Duque, R. Javed, B. S. Phinney, V. Deretic

This study shows ATG5 and membrane atg8ylation regulate retromer function in GLUT1 trafficking, independent of canonical autophagy.

bioRxiv · Jul 10, 2024Cell Biology

Ambroxol and Ciprofloxacin Show Activity Against SARS-CoV2 in Vero E6 Cells at Clinically-Relevant Concentrations

G. S. Timmins, S. B. Bradfute, V. Deretic, S. Kumar, E. C. Clarke, C. Ye

The paper tests drug activity against SARS-CoV-2 in Vero E6 cells and finds ambroxol and ciprofloxacin effective at clinically relevant concentrations.

bioRxiv · Aug 11, 2020 · PreprintMicrobiology

Azithromycin and ciprofloxacin have a chloroquine-like effect on respiratory epithelial cells

V. Deretic, G. S. Timmins

The paper shows that azithromycin and ciprofloxacin, like chloroquine, affect intracellular pH in respiratory epithelial cells, suggesting potential therapeutic relevance in COVID-19.

bioRxiv · Mar 29, 2020 · PreprintMicrobiology