Author

V. G. Fowler

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 3 Assay:bulk RNA-seq· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Approach:statistical model· 2 Organism:bacteria (other)· 1

Frequent Co-Authors

A. A. Ojewole· 1 shared A. Hoffman· 1 shared A. S. Bayer· 1 shared A. S. Meyer· 1 shared B. Conlon· 1 shared B. P. Howden· 1 shared B. R. Donald· 1 shared C. Bouchiat· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperBiochemistry

A. A. Ojewole

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Cytokine-expression patterns reveal coordinated immunological programs associated with persistent MRSA bacteremia

J. L. Chin, Z. C. Tan, L. C. Chan, F. Ruffin, R. Parmar, R. Ahn, S. Taylor, A. S. Bayer, A. Hoffman, V. G. Fowler, E. F. Reed, M. R. Yeaman, A. S. Meyer, MRSA Systems Immunobiology Group

This study uses tensor-based integration of host transcriptional and proteomic data to identify immunological patterns associated with persistent MRSA bacteremia outcomes.

bioRxiv · Dec 28, 2022 · PreprintImmunology

All Staphylococcus aureus bacteraemia strains have the potential to cause infective endocarditis: results of GWAS and experimental animal studies

S. Bastien, S. Meyers, W. Salgado-Pabon, S. Giulieri, J.-P. Rasigade, L. Liesenborghs, K. J. Kinney, F. Couzon, P. Martin-Simoes, V. Le Moing, X. M. Duval, N. E. Holmes, N. E. Bruun, R. Skov, B. P. Howden, , F. Vandenesch

This study shows that all Staphylococcus aureus bacteraemia strains can cause infective endocarditis, as no genetic differences were found between IE and non-IE strains using GWAS and experimental models.

bioRxiv · May 16, 2022 · PreprintMicrobiology

Macrophage-produced peroxynitrite induces antibiotic tolerance and supersedes intrinsic mechanisms of persister formation

J. E. Beam, N. J. Wagner, J. C. Shook, E. S. M. Bahnson, V. G. Fowler, S. E. Rowe, B. Conlon

This study shows that macrophage-produced peroxynitrite induces antibiotic tolerance in S. aureus, overriding intrinsic persister formation mechanisms observed in pure culture.

bioRxiv · May 20, 2021Microbiology

Chiral evasion and stereospecific antifolate resistance in Staphylococcus aureus

S. Wang, S. M. Reeve, A. A. Ojewole, M. S. Frenkel, G. T. Holt, P. Gainza, S. Keshipeddy, V. G. Fowler, D. L. Wright, B. R. Donald

The paper investigates how a mutation in Staphylococcus aureus dihydrofolate reductase affects antifolate resistance and NADPH isomerism through chiral evasion mechanisms.

bioRxiv · Jul 28, 2020Biochemistry