A. Hoffman

GPR4 knockout attenuates intestinal inflammation and forestalls the development of colitis-associated colorectal cancer in murine models

This study shows GPR4 knockout reduces intestinal inflammation and tumor development in colitis-associated colorectal cancer mouse models.

Cytokine-expression patterns reveal coordinated immunological programs associated with persistent MRSA bacteremia

This study uses tensor-based integration of host transcriptional and proteomic data to identify immunological patterns associated with persistent MRSA bacteremia outcomes.

"How do we do this at a distance?!" A descriptive study of remote undergraduate research programs during COVID-19

This study describes and evaluates remote undergraduate research programs in life sciences during the COVID-19 pandemic, identifying strengths, weaknesses, and recommendations for improvement.

Dysbiosis in a canine model of human fistulizing Crohn’s disease

The paper compares gut microbiomes of dogs with canine anal furunculosis to healthy dogs, finding similarities to human Crohn’s disease microbiomes and supporting dogs as a model for studying fistulizing CD.

Broad spectrum proteomics analysis of the inferior Colliculus following acute hydrogen sulfide exposure

This study uses proteomics to identify molecular changes in the mouse inferior colliculus after acute hydrogen sulfide exposure, revealing disrupted biological processes and validated transcriptional changes.