Author

V. Mathew

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. S. Tam· 2 shared A. K. Hofmann· 1 shared A. Karsan· 1 shared A. Kumar· 1 shared A. Shanks· 1 shared A. Y. M. Gu· 1 shared C. A. H. Thompson· 1 shared C. J. Loewen· 1 shared

Activity by Year

2017-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersCell Biology

A. S. Tam

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

DYNLL1 mis-splicing is associated with replicative genome instability in SF3B1 mutant cells

A. S. Tam, S. Tsai, E. Y.-C. Chang, V. Mathew, A. Shanks, T. R. Docking, A. Kumar, D. G. Bernard, A. Karsan, P. C. Stirling

This study shows SF3B1 mutations cause DYNLL1 mis-splicing, leading to genome instability through altered DNA repair and PARP inhibitor sensitivity.

bioRxiv · May 26, 2021 · PreprintCell Biology

Transient telomerase inhibition alters cell cycle kinetics

C. A. H. Thompson, A. Y. M. Gu, S. Y. Yang, V. Mathew, H. Fleisig, J. M. Y. Wong

This study shows that transient telomerase inhibition delays cell cycle progression by inducing ATM-dependent DNA damage signals at telomeres in telomerase-positive cancer cells.

bioRxiv · Aug 25, 2017Cancer Biology

Genotoxin-induced transcriptional repression regulates selective protein aggregation

V. Mathew, A. S. Tam, K. L. Milbury, A. K. Hofmann, C. S. Hughes, G. B. Morin, C. J. Loewen, P. Stirling

The paper investigates how genotoxin-induced transcriptional repression affects protein aggregation by studying the splicing factor Hsh155 under alkylation stress.

bioRxiv · Mar 15, 2017Cell Biology