Author

A. S. Tam

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

V. Mathew· 2 shared A. K. Hofmann· 1 shared A. Karsan· 1 shared A. Kumar· 1 shared A. Shanks· 1 shared C. J. Loewen· 1 shared C. S. Hughes· 1 shared D. G. Bernard· 1 shared

Activity by Year

2017-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCell Biology

V. Mathew

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintMay 26, 2021

DYNLL1 mis-splicing is associated with replicative genome instability in SF3B1 mutant cells

A. S. Tam, S. Tsai, E. Y.-C. Chang…·P. C. Stirling

This study shows SF3B1 mutations cause DYNLL1 mis-splicing, leading to genome instability through altered DNA repair and PARP inhibitor sensitivity.

DOI 10.1101/2021.05.26.445839

humanbulk RNA-seq

𝕏 PostBluesky

Cell BiologybioRxivMar 15, 2017

Genotoxin-induced transcriptional repression regulates selective protein aggregation

V. Mathew, A. S. Tam, K. L. Milbury…·P. Stirling

The paper investigates how genotoxin-induced transcriptional repression affects protein aggregation by studying the splicing factor Hsh155 under alkylation stress.

DOI 10.1083/jcb.201612018

proteomicsDNA methylation

𝕏 PostBluesky