The molecular mechanism and physiological role of silent nociceptor activation
T. A. Nees, N. Wang, P. Adamek, C. Verkest, C. LaPorta, I. Schaefer, J. Virnich, S. Balkaya, V. Prato, C. Morelli, N. Zeitzschel, V. Begay, Y. J. Lee, A. Tappe-Theodor, G. R. Lewin, , S. G. Lechner
This study identifies TMEM100 as a key regulator of silent nociceptor activation during inflammation and shows its role in inducing remote pain hypersensitivity.
bioRxiv · Apr 7, 2022 · PreprintNeuroscience