BioengineeringbioRxiv
Genome-scale metabolic rewiring to achieve predictable titers rates and yield of a non-native product at scale
D. Banerjee, T. T. Eng, A. K. Lau…·A. Mukhopadhyay
This study engineers Pseudomonas putida to produce indigoidine with high titer, rate, and yield by coupling product formation with growth through metabolic rewiring and CRISPRi knockdowns.
DOI 10.1038/s41467-020-19171-4