Pharmacology & ToxicologybioRxivPreprint
Correlating the differences in the receptor binding domain of SARS-CoV-2 spike variants on their interactions with human ACE2 receptor
G. Mahalingam, P. Arjunan, Y. Periasami…·S. Marepally
The paper evaluates binding interactions of SARS-CoV-2 spike variants with hACE2 using ELISA and cellular models, finding that N501Y in RBD enhances binding efficiency, particularly distinguishing C.1.2 from Delta.
DOI 10.1101/2022.09.30.510287