Druggable redox pathways against M. abscessus in cystic fibrosis patient-derived airway organoids
S. A. Leon Icaza, S. Bagayoko, R. VERGE, N. Iakobachvili, C. Ferrand, T. Aydogan, C. Bernard, A. Sanchez Dafun, M. Murris-Espin, J. Mazieres, P. J. Bordignon, S. Mazeres, P. Bernes Lasserre, V. Rame, J.-M. Lagarde, , C. Cougoule
This study uses airway organoids to investigate M. abscessus infection in CF patients, showing antioxidant pathways can inhibit bacterial growth and enhance antibiotic efficacy.
bioRxiv · Jan 3, 2022 · PreprintCell Biology