Author

R. Verge

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:drug response / drug discovery· 1 Assay:organoid / primary culture· 1 Assay:proteomics· 1

Frequent Co-Authors

C. Cougoule· 2 shared E. Meunier· 2 shared A. Henras· 1 shared A. Hessel· 1 shared A. Sanchez Dafun· 1 shared C. Bernard· 1 shared C. Chalut· 1 shared C. Ferrand· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersImmunology

C. Cougoule

Mutual co-authors in cluster

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2 papers

Recent·Most cited

EEF2-inactivating toxins engage the NLRP1 inflammasome and promote epithelial barrier disruption upon Pseudomonas infection

M. Pinilla, R. Mazars, R. Verge, L. Gorse, K. Santoni, K. S. Robinson, G. A. Toh, L. Prouvensier, S. A. Leonicaza, A. Hessel, d. pericat, M. Murris, A. Henras, J. M. Buyck, C. Cougoule, , E. Meunier

This paper shows that Pseudomonas aeruginosa's Exotoxin A activates the NLRP1 inflammasome via EEF2 inactivation, causing epithelial damage and pyroptosis, and identifies ZAK as a key sensor in this process.

bioRxiv · Jan 16, 2023 · PreprintImmunology

Druggable redox pathways against M. abscessus in cystic fibrosis patient-derived airway organoids

S. A. Leon Icaza, S. Bagayoko, R. VERGE, N. Iakobachvili, C. Ferrand, T. Aydogan, C. Bernard, A. Sanchez Dafun, M. Murris-Espin, J. Mazieres, P. J. Bordignon, S. Mazeres, P. Bernes Lasserre, V. Rame, J.-M. Lagarde, , C. Cougoule

This study uses airway organoids to investigate M. abscessus infection in CF patients, showing antioxidant pathways can inhibit bacterial growth and enhance antibiotic efficacy.

bioRxiv · Jan 3, 2022 · PreprintCell Biology