Author

C. Chalut

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 2 Organism:bacteria (other)· 1 Research Focus:drug response / drug discovery· 1 Assay:organoid / primary culture· 1

Frequent Co-Authors

C. Guilhot· 2 shared S. Mazeres· 2 shared A. Sanchez Dafun· 1 shared C. Astarie-Dequeker· 1 shared C. Bernard· 1 shared C. Cougoule· 1 shared C. Ferrand· 1 shared D. A. Russell· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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2 shared papersCell Biology

C. Guilhot

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Mycobacterium trehalose polyphleates are required for infection by therapeutically useful mycobacteriophages BPs and Muddy

K. S. Wetzel, M. Illouz, L. Abad, H. G. Aull, D. A. Russell, R. A. Garlena, M. Cristinziano, S. Malmsheimer, C. Chalut, G. F. Hatfull, L. Kremer

This study shows that trehalose polyphleates are essential for phage infection of Mycobacterium species and that phage resistance can arise through TPP loss or mutations in phage tail spike proteins.

bioRxiv · Mar 14, 2023Microbiology

Druggable redox pathways against M. abscessus in cystic fibrosis patient-derived airway organoids

S. A. Leon Icaza, S. Bagayoko, R. VERGE, N. Iakobachvili, C. Ferrand, T. Aydogan, C. Bernard, A. Sanchez Dafun, M. Murris-Espin, J. Mazieres, P. J. Bordignon, S. Mazeres, P. Bernes Lasserre, V. Rame, J.-M. Lagarde, , C. Cougoule

This study uses airway organoids to investigate M. abscessus infection in CF patients, showing antioxidant pathways can inhibit bacterial growth and enhance antibiotic efficacy.

bioRxiv · Jan 3, 2022 · PreprintCell Biology

Phthiocerol dimycocerosates from Mycobacterium tuberculosis increase the membrane activity of bacterial effectors and host receptors

J. Augenstreich, E. Haanappel, F. Sayes, R. Simeone, V. Guillet, S. Mazeres, C. Chalut, L. Mourey, R. Brosch, C. Guilhot, C. Astarie-Dequeker

This study shows that phthiocerol dimycocerosates (DIM) from Mycobacterium tuberculosis increase membrane activity of both bacterial effectors and host receptors, aiding immune evasion.

bioRxiv · May 13, 2020Microbiology