Author

V. Sottas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 1

Signature Assays, Organisms & Methods

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Assay:electrophysiology· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

A. Hudmon· 1 shared A. Shestak· 1 shared D. Ross-Kaschitza· 1 shared E. V. Zaklyazminskaya· 1 shared G. S. Pitt· 1 shared H. Abriel· 1 shared J.-S. Rougier· 1 shared S. H. Vermij· 1 shared

Activity by Year

2020-2020 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperPhysiology

A. Hudmon

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1 paper

Recent·Most cited

Calmodulin binds to the N-terminal domain of the cardiac sodium channel Nav1.5

Z. Wang, S. H. Vermij, V. Sottas, A. Shestak, D. Ross-Kaschitza, E. V. Zaklyazminskaya, A. Hudmon, G. S. Pitt, J.-S. Rougier, H. Abriel

This study identifies calmodulin as a new binding partner of the Nav1.5 N-terminal domain and shows that mutations in this region impair the interaction, contributing to dominant-negative effects in Brugada Syndrome.

bioRxiv · Jun 2, 2020Physiology