Cancer BiologybioRxiv
A Multifactorial Model of T Cell Expansion and Durable Clinical Benefit in Response to a PD-L1 Inhibitor
M. D. Leiserson, V. Syrgkanis, A. Gilson…·L. Mackey
This paper develops a multifactorial model to predict T cell expansion and clinical benefit from PD-L1 inhibitors using clinical, tumor, and circulating features, showing improved accuracy over single biomarkers.
DOI 10.1371/journal.pone.0208422