Caveolae set levels of epithelial monolayer tension to eliminate tumor cells
J. L. C. Teo, G. A. Gomez, I. Noordstra, S. Verma, V. Tomatis, B. R. Acharya, L. Balasubramaniam, H. Katsuno-Kambe, R. Templin, K.-A. McMahon, R. J. Ju, S. J. Stebhens, B. Ladoux, R. G. Parton, A. S. Yap
The paper shows caveolae regulate epithelial tension through lipid signaling, enabling the elimination of oncogene-transformed cells by apical extrusion.
bioRxiv · May 9, 2019 · PreprintCell Biology