Author

Valentina Krendelshchikova

Duke University

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Neuroscience· 1

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Andrew B. WestiD· 1 shared Arpine SokratianiD· 1 shared Ashley S. HarmsiD· 1 shared Aubrey M SchonhoffiD· 1 shared Enquan XuiD· 1 shared Hisham AbdelmotilibiD· 1 shared Irene E. HarmseniD· 1 shared Kaela KellyiD· 1 shared

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2020-2020 · peak 1/yr

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1 shared paperNeuroscience

Andrew B. WestORCID

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1 paper

Recent·Most cited

NeurosciencebioRxivPreprintMay 4, 2020

Pathologic α-Synuclein Species Activate LRRK2 in Pro-Inflammatory Monocyte and Macrophage Responses

Enquan Xu, Ravindra Boddu, Hisham Abdelmotilib…·Andrew B. West

The paper shows that α-synuclein fibrils activate LRRK2 kinase in monocyte-derived macrophages, linking LRRK2 mutations to pro-inflammatory responses in Parkinson's disease.

1 citation

humanmouse

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