ImmunologyiSciencePeer-reviewed
Linear ubiquitin chain assembly complex contributes to NLRP3-mediated pyroptotic cell death
Tiphaine Douanne, Rosalie Moreau, Valeria Trapani…·Nicolas Bidère
This study shows that linear ubiquitination, mediated by LUBAC, is essential for the execution phase of NLRP3-mediated pyroptosis, independent of priming.