Cell BiologybioRxivPreprint
SUN2 mediates epigenetic remodeling to drive mechanotransduction during skin fibrosis
Aya Nassereddine, Kerri A. Davidson, Sandra Sandria…·Valerie Horsley
This study identifies SUN2 as a mediator of nuclear mechanosensing in fibrosis, showing it drives chromatin remodeling and fibrotic gene expression in response to mechanical stiffness.