BioengineeringScience AdvancesPeer-reviewed
De Novo Design of Peptide Binders to Conformationally Diverse Targets with Contrastive Language Modeling
Suhaas Bhat, Kalyan Palepu, Lauren Hong…·Pranam Chatterjee
This paper designs short, target-binding linear peptides using a contrastive learning framework, demonstrating effective binding and degradation of conformationally diverse proteins.
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