Cancer BiologyEJNMMI ResearchPeer-reviewed
Non-invasive visualization of pH changes within the tumor-micro-environment by positron emission tomography
Jürgen Brück, Dominik Schauenburg, Seah Ling Kuan…·Matthias Miederer
This paper develops a PET-based method to visualize pH changes in the tumor microenvironment using [18F]FDG-4MBA, showing it can detect small pH differences in different tumors in the same mouse.