Molecular BiologyPLoS GeneticsPeer-reviewed
Defining transcription factor nucleosome binding with Pioneer-seq
Maria Tsompana, Patrick D. Wilson, Vijaya Murugaiyan…·Michael Joseph Buck
This study introduces Pioneer-seq to analyze TF nucleosome binding and finds that KLF4 and SOX2 bind near the nucleosome dyad, with nucleosome sequence being the major determinant of TF binding.
6 citations