Synthetic BiologybioRxivPreprint
✦ In-depth digest
Chai-1: Decoding the molecular interactions of life
Chai Discovery, Jacques Boitreaud, Jack Dent…·Kevin Wu
Chai-1 matches AlphaFold3 on PoseBusters ligand poses (77% vs 76%), beats AlphaFold-Multimer 2.3 on low-homology interfaces, and stays competitive without MSAs on multimers and antibodies.
443 citations