Author

Vishaka Santosh

Virginia Commonwealth University

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Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Alexander Washington· 1 shared Brandon Braud· 1 shared Carlos R. EscalanteiD· 1 shared Karen C. Hernández-Ramírez· 1 shared Rahul JaiswaliD· 1 shared

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2025-2025 · peak 1/yr

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1 shared paperBiochemistry

Alexander Washington

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1 paper

Recent·Most cited

BiochemistryNucleic Acids ResearchPeer-reviewedJan 17, 2025

Cryo-EM Structure of AAV2 Rep68 bound to integration site AAVS1: Insights into the mechanism of DNA melting

Rahul Jaiswal, Brandon Braud, Karen C. Hernández-Ramírez…·Carlos R. Escalante

The paper reports Cryo-EM structures of AAV2 Rep68 bound to DNA at the AAVS1 integration site, revealing conformational changes and DNA distortion mechanisms during replication.

9 citations

cryo-EMexperimental assay

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